About the show
Identical twins, Tia Landry and Tamera Campbell, were separated by adoption at birth after their biological mother died. However, fourteen years later, they find each other by accident at a clothing store at the mall with their adoptive parents. After their chance encounter, Ray Campbell, Tamera's adoptive father, reluctantly allows Tia and her adoptive mother Lisa Landry to move in with them so the girls had the opportunity to reconnect.
Although the twins are identical in appearance their personalities are polar opposites, with Tia being the intelligent one from inner city Detroit while Tamera is the boy-crazy twin from the suburbs. The series follows the sisters as they go through high school and reconnect as sisters.
- Tia Mowry as Tia Landry
- Tamera Mowry as Tamera Campbell
- Jackée Harry as Lisa Landry
- Tim Reid as Ray Campbell
- Marques Houston as Roger Evans
- RonReaco Lee as Tyreke Scott
- Deon Richmond as Jordan Bennet
ABC had picked up Sister, Sister as a midseason replacement, where it debuted on April 1, 1994. For the 1994–95 season, the show moved to another timeslot, though due to low ratings, its final episode on ABC of the show aired on April 28, 1995, after which the show was picked up by WB, where the series' last 4 seasons aired.