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Desperate Housewives is an ABC network comedy-drama\mystery series created by Marc Cherry which aired from October 3, 2004 to May 13, 2012, lasting for 8 seasons & 180 episodes.
Set on Wisteria Lane, a street in the fictional town of Fairview in the fictional Eagle State, the series followed the lives of a group of women as seen through the eyes of Mary Alice Young, their late friend and neighbor who committed suicide in the pilot episode.
The show's storyline covers thirteen years of the women's lives over eight seasons, set between the years 2004–2008 and later 2013–2017 (the story arc included a five-year passage of time as well as flashbacks ranging from the 1980s to the 2020s).
The women worked through domestic struggles and family life while facing the secrets, crimes and mysteries hidden behind the doors of their (on the surface) beautiful and seemingly perfect suburban neighborhood.
The show's first season introduced the four central characters of the show: Susan Mayer, Lynette Scavo, Bree Van de Kamp and Gabrielle Solis as well as their families and neighbors on Wisteria Lane.
The main mystery of the season is the unexpected suicide of Mary Alice Young, and the involvement of her husband Paul Young (Mark Moses) and their son Zach (Cody Kasch) in the events leading up to it.
Susan fights Edie Britt (Nicollette Sheridan) for the affection of new neighbor Mike Delfino (James Denton), Lynette struggles to cope with her demanding children, Bree fights to save her marriage to Rex Van de Kamp (Steven Culp) and Gabrielle tries to prevent her husband Carlos Solis (Ricardo Antonio Chavira) from discovering that she is having an affair with their gardener, John Rowland (Jesse Metcalfe).
The second season's central mystery was about new neighbor Betty Applewhite (Alfre Woodard), who moved onto Wisteria Lane in the middle of the night.
Throughout the season, Bree tries to cope with being a widow, unknowingly begins dating the man who poisoned her husband, fights alcoholism and is unable to prevent the gap between her and her son Andrew Van de Kamp (Shawn Pyfrom) from growing to extremes.
Susan's love life becomes even more complicated as her ex-husband Karl Mayer (Richard Burgi) is engaged to Edie and is also started to incline towards Susan.
Lynette goes back to her career in advertising while her husband Tom Scavo (Doug Savant) becomes a stay-at-home father. Gabrielle decides to be faithful to Carlos, and begins preparations to have a child. Paul is framed and sent to jail not for the murder he committed in the previous season, but for a fake one.
In the show's third season, Bree marries Orson Hodge (Kyle MacLachlan), whose past and involvement with a recently discovered dead body becomes the main mystery of the season. Meanwhile, Lynette has to adjust to the arrival of Tom's previously unknown daughter, Kayla to the home.
The Scavos also experience tension as Tom wants to start a pizzeria. Gabrielle goes through a rough divorce, but finally finds new love in Fairview's new mayor.
After being run over by Orson in the previous season finale, Mike falls into a coma and suffers from amnesia when he wakes up. Edie sees her chance to make her move on Mike, and her family relations are explored throughout the season.
Susan loses hope that Mike's memory will return and in the process moves on to a handsome Englishman whose wife is also in a coma while her daughter Julie Mayer (Andrea Bowen) starts dating Edie's nephew. Elderly neighbor Karen McCluskey (Kathryn Joosten) hides something in her freezer. A shooting at the local grocery store leaves two characters dead and changes everyone's lives forever.
The fourth season's main mystery revolved around new neighbor Katherine Mayfair (Dana Delany) and her family, who return to Wisteria Lane after twelve years away.
Lynette battles cancer; the newlywed (but unhappy) Gabrielle starts an affair with her ex-husband Carlos; Susan and Mike enjoy life as a married couple and learn that they are expecting a child; Bree fakes a pregnancy and plans to raise her teenage daughter's illegitimate child as her own; and Edie schemes to hold on to her new love, Carlos. A gay couple from Chicago: Lee McDermott (Kevin Rahm) and Bob Hunter (Tuc Watkins) become residents of Wisteria Lane.
A tornado threatens to destroy everything, and everyone, that the housewives hold dear. In the closing minute the characters and their story have flashed forward by five years.
The fifth season jumps five years after the previous season with some flashbacks to events which happened between the two periods.
The mystery of the season revolves around Edie's new husband, Dave Williams (Neal McDonough), who is looking for revenge on someone on Wisteria Lane (later revealed to be Mike).
Susan deals with being a single mother and having a new romance with her painter, while Mike starts dating Katherine. Lynette and Tom learn that their now teenage son is having an affair with a married woman whose husband's nightclub burns down with all of Wisteria Lane's neighbors inside.
Gabrielle struggles with Carlos' blindness, two young daughters, and a financial crisis. Bree and Orson have marriage problems because Bree has become too focused on her career as a successful cookbook writer and caterer. Edie dies of electrocution after a car crash, before she can expose Dave moments after she discovers his secret.
The sixth season's main mystery of this season is surrounding new neighbor Angie Bolen (Drea de Matteo) and her family. The first half of the season consists of Julie being strangled by an unknown person, the conflict between Gabrielle and her niece Ana Solis (Maiara Walsh), Lynette's attempt to sue her new boss Carlos, Katherine's eventual breakdown at losing Mike to Susan and Bree's affair with Karl which ends tragically when Karl's hired plane crashes into a building with the two of them and Orson inside.
The second half of the season focuses on Katherine experimenting with her sexuality, Lynette inviting the Fairview strangler to stay with them before discovering the truth, the conflict between Bree and a son of Rex whom he had before meeting Bree, and the solving of the Bolen mystery.
The seventh season's main mystery is Paul's return to Wisteria Lane with a new wife and with plans of punishing the residents for shunning him during his incarceration while an old nemesis of his still plans to get her own revenge on him.
Lynette's best friend from college Renee Perry (Vanessa Williams) moves to the lane and stirs things up among the other housewives. Gabrielle and Carlos learn an unsettling fact about their daughter Juanita Solis (Madison De La Garza) which ultimately takes them back to Gabrielle's home town of Las Colinas.
A now divorced Bree starts dating her contractor and reveals the truth about the death of Carlos' mother, consequently ending the friendship between the Solis family and Bree.
Due to financial problems, Susan and her family have moved off the lane & she is forced to earn money by untraditional means. Following a major riot on the lane, Susan is put on the waiting list for a vital organ donation. Lynette persuades Tom to take an exciting new job, which leads to unprecedented problems in their marriage.
The eighth and final season's main mystery of the season is the death of Gabrielle's perverted stepfather Alejandro Perez (Tony Plana) at Carlos' hands and its cover-up by the four housewives which occurred in the previous season finale.
After the murder, Bree receives a blackmail letter from an unknown person similar to the one Mary Alice had received in the first season. Due to her relationship with detective Chuck Vance (Jonathan Cake), Bree becomes the main character affected by the cover-up of Alejandro's murder, and is eventually accused of killing Alejandro herself.
A new neighbor, Ben Faulkner (Charles Mesure), moves into the lane, attracting Renee along the way. Ben is going through severe financial problems and resorts to a dangerous and unruly loan shark to bail him out. Mike meddles in the business of Ben's loan shark in an attempt to protect Renee, but he pays the ultimate price.
During the first half of the season, Susan struggles with the guilt of her involvement in the Alejandro case, and during the second half, she tries to deal with both Julie's unexpected pregnancy and Mike's death.
Following the cover-up of Alejandro's murder, Carlos develops an alcohol problem, but Gabrielle persuades him to recover in rehab which eventually results in Gabrielle & Carlos switching house roles.
Tom moves out of the family home and Lynette struggles to come to terms with how quickly Tom seems to have moved on until she accepts that she is still in love with him & decides she will try to win him back.
Mrs. McCluskey receives worrying news about her health and decides to end it all, but Bree manages to convince her otherwise.
The two-hour series finale (which aired on Sunday, May 13, 2012) featured the conclusion of Bree's court case. To bring the series to a conclusion, there was a wedding, a birth, a death and the future of the four main housewives was revealed.