Brothers & Sisters is an American television drama series that centers on the Walker family and their lives in Pasadena, California. The series premiered on ABC on September 24, 2006, and aired its final episode on May 8, 2011. It aired, for its entire run, in a Sunday night timeslot after Desperate Housewives.
The series revolves around the lives and problems of the wealthy Walker family in the wake of the death of family patriarch William Walker (Tom Skerritt), the founder of the family business Ojai Foods.
The family consists of wife and mother Nora Walker (Sally Field) who must deal with revelations about her husband's infidelity, and her children Sarah (Rachel Griffiths) and Tommy (Balthazar Getty), both married executives at Ojai Foods, Kitty (Calista Flockhart), a conservative activist, Kevin (Matthew Rhys), a gay lawyer, and youngest sibling Justin (Dave Annable), who has recently returned from the Iraq War with a substance abuse problem. They were joined by Nora's brother Saul (Ron Rifkin) and Holly Harper (Patricia Wettig), William's mistress. Plotlines typically revolved around the romantic relationships of the family, their business fortunes, especially with regard to the control of Ojai Foods, and the relationship between the siblings. Most conflicts were resolved with a renewed call for family unity and a lot of wine.